MyBioSource.com's DSG1 antibody is a Mouse monoclonal antibody. The DSG1 antibody was generated using Desmoglein 1, DG1, DSG, DSG1, and PPKS1 as the antigen. It reacts with Human.
Description
Mouse monoclonal DSG1 antibody
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, four desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus